It’s time for a weekend with the boys! Gather your crew and hit the road for a guys’ getaway in St. Charles, MO. Whether you're looking for live music, friendly competition, local history, or great places to grab a drink, you'll find plenty to fill your itinerary. Use the ideas below to start planning, then explore our places to stay, restaurants, and shops to round out your weekend.

Ameristar Casino Resort Spa
Head to Ameristar Casino Resort Spa for a night packed with fun. Try your luck with the latest slot machines, video poker, and table games, or visit the Fanatics Sportsbook to catch the game. Challenge the guys to a round in the Topgolf Swing Suite, then unwind at aRa Spa with its indoor and outdoor pools. As the sun sets, catch live music at the Bottleneck Blues Bar, enjoy drinks at globar, or dance the night away at RYSE Nightclub. When the fun winds down, spend the night in one of Ameristar's contemporary guest rooms so you're ready for another day of adventure.

Local Breweries, Distilleries, & Nightlife
Raise a glass with the guys at some of Saint Charles' favorite watering holes. Sip locally crafted beer at Old Millstream Inn and Good News Brewing, sample handcrafted spirits at Cardinal Sin, or venture into Historic Missouri Wine Country to enjoy locally made vodka, brandy, and other spirits at Judgment Tree Spirits and Stone Ledge Distillery. In Frenchtown, Naked Tiki serves tropical cocktails featuring its house-made rum, while LIT Pipe and Cigar, one of America's oldest tobacco shops, is the perfect place to unwind with a premium cigar. Taste your way through local breweries and distilleries to discover the flavors that make the area unique.

Indoor Recreation & Games
Keep the friendly competition going no matter the weather at Saint Charles' indoor recreation spots. Race each other to the top of the climbing walls at Climb So iLL, challenge your buddies to retro arcade games while enjoying a pint of local beer at Two Plumbers Brewery + Arcade, and battle zombies together in Rec Hall's Zero Latency virtual reality experience. Golf enthusiasts can book a simulator bay at Gimme Golf Club, then celebrate the winner with a drink at its in-house bar, Loopers. If your group prefers racquet sports, head to Chicken N Pickle, where indoor and outdoor pickleball courts, a full-service restaurant, multiple bars, and a rooftop patio make for a fun outing.

Live Music & Entertainment
No guys' getaway is complete without a night out. Catch live music throughout St. Charles, from local favorites like Main Street Honky Tonk and The Midwestern on Historic Main Street to free outdoor concerts during the summer. If you're visiting in the summer or the fall, check the schedules for Music on Main, Hot Summer Nights, and the Beale Street Concert Series to enjoy live performances outside. The fun doesn’t stop there, the Funny Bone at the Streets of St. Charles will keep you and the boys laughing all night long with their lineup of talented stand-up comedians.

History Tours & Museums
If your crew is full of history buffs, you’re in the right place! As the oldest settlement on the Missouri River, Saint Charles played a pivotal role in the westward expansion of the United States. Step back in time on a “Hit the Bricks” walking tour, where view masters reveal what Main Street St. Charles looked like in centuries past, or uncover the city’s darker side on the Macabre Main Street tour, featuring true tales of crime, villainy, and paranormal. Don’t forget to stop at museums in St. Charles! Admire classic and collector cars at Fast Lane Classic Cars, explore decades of soda history at The Soda Museum, and learn more about the Corps of Discovery at the Lewis & Clark Boat House & Museum.

Outdoor Adventures
Get some fresh air with the boys in St. Charles. Rent bikes from Bike Stop Café or Juiced Wheels and cruise along the scenic Katy Trail, cast a line in one of the stocked fishing ponds at the August A. Busch Memorial Conservation Area, or hit the trails for a hike in St. Charles.

Plan Your Guys’ Trip to St. Charles, MO
Are you ready to get the guys together? A guys' trip to St. Charles, MO offers something for every type of traveler. Spend the day exploring Historic Main Street, challenging each other to friendly competitions, or discovering the area's rich history before unwinding with great food, drinks, and live music. Start planning your St. Charles weekend getaway today by exploring our places to stay, restaurants, things to do, and events pages to build an itinerary your best buds won't forget.